(betaS)-beta-amino-2-fluorobenzenepropanoic acid

(betaS)-beta-amino-2-fluorobenzenepropanoic acid - Names and Identifiers

Name	(S)-3-Amino-3-(2-fluoro-phenyl)-propionic acid
Synonyms	H-b-Phe(2-F)-OH H-BETA-PHE(2-F)-OH RARECHEM LK HC T305 H-D-PHG(2-F)-(C*CH2)OH H-D-BETA-HOMOPHG(2-F)-OH (S)-beta-2-Fluorophenylalanine (3S)-3-amino-3-(2-fluorophenyl)propanoic acid (S)-3-Amino-3-(2-fluoro-phenyl)-propionic acid (S)-3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID (betaS)-beta-amino-2-fluorobenzenepropanoic acid
CAS	151911-32-9
InChI	InChI=1/C9H10FNO2/c10-7-4-2-1-3-6(7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

(betaS)-beta-amino-2-fluorobenzenepropanoic acid - Physico-chemical Properties

Molecular Formula	C9H10FNO2
Molar Mass	183.18
Density	1.289±0.06 g/cm3(Predicted)
Boling Point	302.6±32.0 °C(Predicted)
Flash Point	136.8°C
Vapor Presure	0.000434mmHg at 25°C
pKa	3.67±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.554

(betaS)-beta-amino-2-fluorobenzenepropanoic acid - Introduction

(S)-3-Amino-3-(2-fluoro-phenyl)-propionic acid, also known as (S)-FAP-propionic acid, is a stereoisomeric compound. The following is a description of its nature, use, formulation and safety information:

Nature:
(S)-FAP-propionic acid is a white crystalline solid with special optical activity and optical rotation. Its chemical formula is C9H10FNO2, molecular weight is 179.18.

Use:
(S)-FAP-propionic acid is commonly used as a chiral inducer in chemical synthesis to prepare organic molecules such as chiral drugs and pesticides. It can be used as a chiral intermediate to participate in various organic synthesis reactions to achieve chiral control of the product.

Method: The preparation methods of
(S)-FAP-propionic acid include Chiral separation and chemical synthesis, of which chemical synthesis is more commonly used. A typical preparation method is through the amide reaction of styrene and 2-fluorobenzaldehyde, after reduction and carboxylation treatment to obtain the target product.

Safety Information:
(S)-FAP-propionic acid needs to be safe during use and storage. It is irritating and corrosive to avoid contact with skin and eyes. Appropriate protective equipment such as lab gloves, goggles and protective clothing shall be worn during operation. At the same time, it should be used in a well-ventilated environment and away from fire sources and oxidants. When handling or disposing, it should be carried out in accordance with the corresponding regulations and guidelines to avoid pollution to the environment.

Last Update：2024-04-09 21:11:58